BDBM50234092 CHEMBL4073637

SMILES: Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O

InChI Key: InChIKey=IWNYVPCMSYWACS-UXQCFNEQSA-N

Data: 4 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50234092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK2 receptor expressed in HEK293T/17 cells by liquid scintillation coun...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK3 receptor expressed in HEK293T/17 cells by liquid scintillation coun...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50234092 (CHEMBL4073637) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)7-2-1-3-8(4-7)18-9-5-10(12(16)17)13-6-9;/h1-4,9-10,13H,5-6H2,(H,14,15)(H,16,17);1H/t9-,10+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair