BDBM50234104 CHEMBL4105498
SMILES: Cc1ccc(O[C@H]2CN[C@@H](C2)C(O)=O)c(c1)C(O)=O
InChI Key: InChIKey=YESCKBUNHXESRW-SCZZXKLOSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50234104 (CHEMBL4105498) | PDB GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m... | J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50234104 (CHEMBL4105498) | PDB GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]NF608 from eGFP-fused recombinant rat full length GluK1 receptor expressed in HEK293T/17 cells by liquid scintillation counting m... | J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus) | BDBM50234104 (CHEMBL4105498) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK2 receptor expressed in HEK293T/17 cells by liquid scintillation coun... | J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate (Rattus norvegicus) | BDBM50234104 (CHEMBL4105498) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK3 receptor expressed in HEK293T/17 cells by liquid scintillation coun... | J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus) | BDBM50234104 (CHEMBL4105498) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from eGFP-fused recombinant rat full length GluA2 receptor expressed in HEK293T/17 cells by liquid scintillation counti... | J Med Chem 60: 441-457 (2017) BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair |