BDBM50234120 CHEMBL4096695

SMILES: Oc1ccccc1CNn1c(SCc2cc(=O)c(O)co2)nnc1-c1cccc(Cl)c1

InChI Key: InChIKey=FCKWWZJVWINMFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50234120 (CHEMBL4096695) Show SMILES Oc1ccccc1CNn1c(SCc2cc(=O)c(O)co2)nnc1-c1cccc(Cl)c1 Show InChI InChI=1S/C21H17ClN4O4S/c22-15-6-3-5-13(8-15)20-24-25-21(31-12-16-9-18(28)19(29)11-30-16)26(20)23-10-14-4-1-2-7-17(14)27/h1-9,11,23,27,29H,10,12H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Hunan University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 20 mi...				Bioorg Med Chem Lett 27: 530-532 (2017) BindingDB Entry DOI: 10.7270/Q26M392F
					More data for this Ligand-Target Pair