BDBM50234127 CHEMBL4088997

SMILES: Oc1ccccc1CNn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1

InChI Key: InChIKey=JOMYKDIFPVUAKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50234127 (CHEMBL4088997) Show SMILES Oc1ccccc1CNn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1 Show InChI InChI=1S/C21H18N4O4S/c26-17-9-5-4-8-15(17)11-22-25-20(14-6-2-1-3-7-14)23-24-21(25)30-13-16-10-18(27)19(28)12-29-16/h1-10,12,22,26,28H,11,13H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Hunan University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 20 mi...				Bioorg Med Chem Lett 27: 530-532 (2017) BindingDB Entry DOI: 10.7270/Q26M392F
					More data for this Ligand-Target Pair