BDBM50234170 CHEMBL4068963

SMILES: Cn1nc(nc1-c1cnc(N)c(n1)-n1nnc2ccccc12)C1(CC1)c1ccccc1

InChI Key: InChIKey=NNUYQWVLMLAQAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50234170 (CHEMBL4068963) Show SMILES Cn1nc(nc1-c1cnc(N)c(n1)-n1nnc2ccccc12)C1(CC1)c1ccccc1 Show InChI InChI=1S/C22H19N9/c1-30-19(26-21(28-30)22(11-12-22)14-7-3-2-4-8-14)16-13-24-18(23)20(25-16)31-17-10-6-5-9-15(17)27-29-31/h2-10,13H,11-12H2,1H3,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...				Bioorg Med Chem Lett 27: 679-687 (2017) BindingDB Entry DOI: 10.7270/Q2TF00MM
					More data for this Ligand-Target Pair