BDBM50234171 CHEMBL4090043

SMILES: Nc1ncc(nc1-n1nnc2ccccc12)-c1n[nH]c(n1)C1(CC1)c1ccccc1

InChI Key: InChIKey=JZHMIGXHVXMYEX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50234171 (CHEMBL4090043) Show SMILES Nc1ncc(nc1-n1nnc2ccccc12)-c1n[nH]c(n1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C21H17N9/c22-17-19(30-16-9-5-4-8-14(16)26-29-30)24-15(12-23-17)18-25-20(28-27-18)21(10-11-21)13-6-2-1-3-7-13/h1-9,12H,10-11H2,(H2,22,23)(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...				Bioorg Med Chem Lett 27: 679-687 (2017) BindingDB Entry DOI: 10.7270/Q2TF00MM
					More data for this Ligand-Target Pair