BDBM50234509 4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one::CHEMBL256072

SMILES: Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(C)c2Cl)cc[nH]c1=O)N1CCOCC1

InChI Key: InChIKey=GLISBSFAODYFPL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50234509 (4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(C)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C23H26ClN7O2/c1-14-11-15(31-7-9-33-10-8-31)12-18-20(14)29-22(28-18)19-16(3-6-26-23(19)32)25-5-4-17-21(24)30(2)13-27-17/h3,6,11-13H,4-5,7-10H2,1-2H3,(H,28,29)(H2,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 1702-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.049 BindingDB Entry DOI: 10.7270/Q2NV9J1M
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50234509 (4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(C)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C23H26ClN7O2/c1-14-11-15(31-7-9-33-10-8-31)12-18-20(14)29-22(28-18)19-16(3-6-26-23(19)32)25-5-4-17-21(24)30(2)13-27-17/h3,6,11-13H,4-5,7-10H2,1-2H3,(H,28,29)(H2,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 after 20 mins by BFC fluorescence assay				Bioorg Med Chem Lett 20: 1744-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.087 BindingDB Entry DOI: 10.7270/Q2MW2H95
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50234509 (4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(C)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C23H26ClN7O2/c1-14-11-15(31-7-9-33-10-8-31)12-18-20(14)29-22(28-18)19-16(3-6-26-23(19)32)25-5-4-17-21(24)30(2)13-27-17/h3,6,11-13H,4-5,7-10H2,1-2H3,(H,28,29)(H2,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant IGF-1R tyrosine kinase expressed in baculovirus system assessed as [33gamma]ATP phosphorylation of poly(Glu/Tyr) subs...				Bioorg Med Chem Lett 20: 1744-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.087 BindingDB Entry DOI: 10.7270/Q2MW2H95
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50234509 (4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(C)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C23H26ClN7O2/c1-14-11-15(31-7-9-33-10-8-31)12-18-20(14)29-22(28-18)19-16(3-6-26-23(19)32)25-5-4-17-21(24)30(2)13-27-17/h3,6,11-13H,4-5,7-10H2,1-2H3,(H,28,29)(H2,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R expressed in SAL cells				Bioorg Med Chem Lett 18: 1702-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.049 BindingDB Entry DOI: 10.7270/Q2NV9J1M
					More data for this Ligand-Target Pair