null

SMILES: Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(CCF)c2Cl)cc[nH]c1=O)N1CCOCC1

InChI Key: InChIKey=BMDWGBKTVZKYCM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50234525 (4-(2-(5-chloro-1-(2-fluoroethyl)-1H-imidazol-4-yl)...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(CCF)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C24H27ClFN7O2/c1-15-12-16(32-8-10-35-11-9-32)13-19-21(15)31-23(30-19)20-17(2-6-28-24(20)34)27-5-3-18-22(25)33(7-4-26)14-29-18/h2,6,12-14H,3-5,7-11H2,1H3,(H,30,31)(H2,27,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	451	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R expressed in SAL cells				Bioorg Med Chem Lett 18: 1702-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.049 BindingDB Entry DOI: 10.7270/Q2NV9J1M
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50234525 (4-(2-(5-chloro-1-(2-fluoroethyl)-1H-imidazol-4-yl)...) Show SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCCc2ncn(CCF)c2Cl)cc[nH]c1=O)N1CCOCC1 Show InChI InChI=1S/C24H27ClFN7O2/c1-15-12-16(32-8-10-35-11-9-32)13-19-21(15)31-23(30-19)20-17(2-6-28-24(20)34)27-5-3-18-22(25)33(7-4-26)14-29-18/h2,6,12-14H,3-5,7-11H2,1H3,(H,30,31)(H2,27,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 1702-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.049 BindingDB Entry DOI: 10.7270/Q2NV9J1M
					More data for this Ligand-Target Pair