BDBM50234575 CHEMBL4101852

SMILES: COc1cncc(c1)C#Cc1cc(ccc1C)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F

InChI Key: InChIKey=FDKDDPDXNMFTRY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50234575 (CHEMBL4101852) Show SMILES COc1cncc(c1)C#Cc1cc(ccc1C)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F Show InChI InChI=1S/C29H29F3N4O2/c1-20-4-6-23(15-22(20)7-5-21-14-26(38-3)18-33-17-21)28(37)34-25-9-8-24(27(16-25)29(30,31)32)19-36-12-10-35(2)11-13-36/h4,6,8-9,14-18H,10-13,19H2,1-3H3,(H,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant KDR (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA method				Eur J Med Chem 126: 122-132 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CQK
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50234575 (CHEMBL4101852) Show SMILES COc1cncc(c1)C#Cc1cc(ccc1C)C(=O)Nc1ccc(CN2CCN(C)CC2)c(c1)C(F)(F)F Show InChI InChI=1S/C29H29F3N4O2/c1-20-4-6-23(15-22(20)7-5-21-14-26(38-3)18-33-17-21)28(37)34-25-9-8-24(27(16-25)29(30,31)32)19-36-12-10-35(2)11-13-36/h4,6,8-9,14-18H,10-13,19H2,1-3H3,(H,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA method				Eur J Med Chem 126: 122-132 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CQK
					More data for this Ligand-Target Pair