BDBM50234576 CHEMBL4083853

SMILES: CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cncc(c3)N3CCN(C)CC3)cc2C(F)(F)F)CC1

InChI Key: InChIKey=MXCIAIOVWVMWIF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50234576 (CHEMBL4083853) Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cncc(c3)N3CCN(C)CC3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C33H37F3N6O/c1-24-4-6-27(19-26(24)7-5-25-18-30(22-37-21-25)42-16-12-40(3)13-17-42)32(43)38-29-9-8-28(31(20-29)33(34,35)36)23-41-14-10-39(2)11-15-41/h4,6,8-9,18-22H,10-17,23H2,1-3H3,(H,38,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant KDR (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA method				Eur J Med Chem 126: 122-132 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CQK
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50234576 (CHEMBL4083853) Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cncc(c3)N3CCN(C)CC3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C33H37F3N6O/c1-24-4-6-27(19-26(24)7-5-25-18-30(22-37-21-25)42-16-12-40(3)13-17-42)32(43)38-29-9-8-28(31(20-29)33(34,35)36)23-41-14-10-39(2)11-15-41/h4,6,8-9,18-22H,10-17,23H2,1-3H3,(H,38,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA method				Eur J Med Chem 126: 122-132 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CQK
					More data for this Ligand-Target Pair