BDBM50234651 4,6-dinitrobenzene-1,2,3-triol::CHEMBL400737
SMILES: Oc1c(O)c(cc(c1O)[N+]([O-])=O)[N+]([O-])=O
InChI Key: InChIKey=JJPIRJNQXIJGPL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Autoinducer 2-binding periplasmic protein luxP (Vibrio harveyi) | BDBM50234651 (4,6-dinitrobenzene-1,2,3-triol | CHEMBL400737) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University Curated by ChEMBL | Assay Description Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrs | Bioorg Med Chem Lett 18: 1567-72 (2008) Article DOI: 10.1016/j.bmcl.2008.01.081 BindingDB Entry DOI: 10.7270/Q2DB81KV | |||||||||||
More data for this Ligand-Target Pair |