BDBM50235088 CHEMBL254564::methyl 2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-2-ylmethoxy)benzoate

SMILES: COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(CC2CCC1C2)c1ccccc1

InChI Key: InChIKey=HTVMFNNDIAJZQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50235088 (CHEMBL254564 | methyl 2-(2-phenylbicyclo[2.2.1]hep...) Show SMILES COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(CC2CCC1C2)c1ccccc1 |w:24.27,27.29,22.33,THB:21:22:26.25:28,TEB:29:22:26.25:28| Show InChI InChI=1S/C31H29NO3/c1-34-30(33)27-16-15-26(35-20-25-14-12-22-7-5-6-10-29(22)32-25)18-28(27)31(23-8-3-2-4-9-23)19-21-11-13-24(31)17-21/h2-10,12,14-16,18,21,24H,11,13,17,19-20H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [125I]L-691831 from FLAP				Bioorg Med Chem Lett 18: 2023-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.105 BindingDB Entry DOI: 10.7270/Q2CV4JKD
					More data for this Ligand-Target Pair