BDBM50235095 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-2-ylmethoxy)phenoxy)acetic acid::CHEMBL256766

SMILES: OC(=O)COc1ccc(OCc2ccc3ccccc3n2)cc1C1(CC2CCC1C2)c1ccccc1

InChI Key: InChIKey=HRALKNODRGSHFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50235095 (2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinol...) Show SMILES OC(=O)COc1ccc(OCc2ccc3ccccc3n2)cc1C1(CC2CCC1C2)c1ccccc1 |w:25.28,28.30,23.34,THB:22:23:27.26:29,TEB:30:23:27.26:29| Show InChI InChI=1S/C31H29NO4/c33-30(34)20-36-29-15-14-26(35-19-25-13-11-22-6-4-5-9-28(22)32-25)17-27(29)31(23-7-2-1-3-8-23)18-21-10-12-24(31)16-21/h1-9,11,13-15,17,21,24H,10,12,16,18-20H2,(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [125I]L-691831 from FLAP				Bioorg Med Chem Lett 18: 2023-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.105 BindingDB Entry DOI: 10.7270/Q2CV4JKD
					More data for this Ligand-Target Pair