BDBM50235133 CHEMBL4071789

SMILES: Oc1cc(O)c(C(=O)\C=C\c2ccc(OCc3ccccc3)cc2)c(O)c1

InChI Key: InChIKey=DCSUYOIYDKRKIC-DHZHZOJOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50235133 (CHEMBL4071789) Show SMILES Oc1cc(O)c(C(=O)\C=C\c2ccc(OCc3ccccc3)cc2)c(O)c1 Show InChI InChI=1S/C22H18O5/c23-17-12-20(25)22(21(26)13-17)19(24)11-8-15-6-9-18(10-7-15)27-14-16-4-2-1-3-5-16/h1-13,23,25-26H,14H2/b11-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Lisboa Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ...				J Med Chem 60: 568-579 (2017) Article DOI: 10.1021/acs.jmedchem.6b01134 BindingDB Entry DOI: 10.7270/Q2KK9F2F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50235133 (CHEMBL4071789) Show SMILES Oc1cc(O)c(C(=O)\C=C\c2ccc(OCc3ccccc3)cc2)c(O)c1 Show InChI InChI=1S/C22H18O5/c23-17-12-20(25)22(21(26)13-17)19(24)11-8-15-6-9-18(10-7-15)27-14-16-4-2-1-3-5-16/h1-13,23,25-26H,14H2/b11-8+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Lisboa Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ...				J Med Chem 60: 568-579 (2017) Article DOI: 10.1021/acs.jmedchem.6b01134 BindingDB Entry DOI: 10.7270/Q2KK9F2F
					More data for this Ligand-Target Pair