BDBM50235273 CHEMBL4084347

SMILES: OC(Cc1cccnc1-c1cccc(c1)C(F)(F)F)(c1cccnc1F)c1cccnc1F

InChI Key: InChIKey=ITQAKSHSWVNJKB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50235273 (CHEMBL4084347) Show SMILES OC(Cc1cccnc1-c1cccc(c1)C(F)(F)F)(c1cccnc1F)c1cccnc1F Show InChI InChI=1S/C24H16F5N3O/c25-21-18(8-3-11-31-21)23(33,19-9-4-12-32-22(19)26)14-16-6-2-10-30-20(16)15-5-1-7-17(13-15)24(27,28)29/h1-13,33H,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.5 (unknown origin)				Bioorg Med Chem Lett 27: 1062-1069 (2017) Article DOI: 10.1016/j.bmcl.2016.12.054 BindingDB Entry DOI: 10.7270/Q2DV1N5F
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50235273 (CHEMBL4084347) Show SMILES OC(Cc1cccnc1-c1cccc(c1)C(F)(F)F)(c1cccnc1F)c1cccnc1F Show InChI InChI=1S/C24H16F5N3O/c25-21-18(8-3-11-31-21)23(33,19-9-4-12-32-22(19)26)14-16-6-2-10-30-20(16)15-5-1-7-17(13-15)24(27,28)29/h1-13,33H,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranes				Bioorg Med Chem Lett 27: 1062-1069 (2017) Article DOI: 10.1016/j.bmcl.2016.12.054 BindingDB Entry DOI: 10.7270/Q2DV1N5F
					More data for this Ligand-Target Pair