BDBM50235538 CHEMBL401261::N-((3-fluoro-4-methylpyridin-2-yl)methyl)-2-(4-methyl-1-(2-(methylsulfonyl)phenylsulfonamido)-2-oxo-1,2-dihydropyridin-3-yl)acetamide

SMILES: Cc1ccnc(CNC(=O)Cc2c(C)ccn(NS(=O)(=O)c3ccccc3S(C)(=O)=O)c2=O)c1F

InChI Key: InChIKey=SLDWMBUXVXPDJD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50235538 (CHEMBL401261 | N-((3-fluoro-4-methylpyridin-2-yl)m...) Show SMILES Cc1ccnc(CNC(=O)Cc2c(C)ccn(NS(=O)(=O)c3ccccc3S(C)(=O)=O)c2=O)c1F Show InChI InChI=1S/C22H23FN4O6S2/c1-14-9-11-27(26-35(32,33)19-7-5-4-6-18(19)34(3,30)31)22(29)16(14)12-20(28)25-13-17-21(23)15(2)8-10-24-17/h4-11,26H,12-13H2,1-3H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 18: 1972-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.122 BindingDB Entry DOI: 10.7270/Q2833SV0
					More data for this Ligand-Target Pair