null

SMILES: CN(C)CCCOc1cn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c2c1C

InChI Key: InChIKey=LTJJQWUFSHDXIN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235556 (1-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...) Show SMILES CN(C)CCCOc1cn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c2c1C Show InChI InChI=1S/C27H28F2N6O4/c1-17-23(38-12-4-11-34(2)3)15-35-25(17)26(30-16-31-35)39-22-10-9-20(14-21(22)29)32-27(37)33-24(36)13-18-5-7-19(28)8-6-18/h5-10,14-16H,4,11-13H2,1-3H3,(H2,32,33,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235556 (1-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...) Show SMILES CN(C)CCCOc1cn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c2c1C Show InChI InChI=1S/C27H28F2N6O4/c1-17-23(38-12-4-11-34(2)3)15-35-25(17)26(30-16-31-35)39-22-10-9-20(14-21(22)29)32-27(37)33-24(36)13-18-5-7-19(28)8-6-18/h5-10,14-16H,4,11-13H2,1-3H3,(H2,32,33,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system				Bioorg Med Chem Lett 18: 1945-51 (2008) Article DOI: 10.1016/j.bmcl.2008.01.121 BindingDB Entry DOI: 10.7270/Q2125SFV
					More data for this Ligand-Target Pair