null

SMILES: CC(=O)NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1

InChI Key: InChIKey=JTZCINZNRFOJCN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235562 (1-(4-(5-((4-acetamidopiperidin-1-yl)methyl)pyrrolo...) Show SMILES CC(=O)NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1 Show InChI InChI=1S/C29H29F2N7O4/c1-18(39)34-22-9-11-37(12-10-22)16-20-8-13-38-27(20)28(32-17-33-38)42-25-7-6-23(15-24(25)31)35-29(41)36-26(40)14-19-2-4-21(30)5-3-19/h2-8,13,15,17,22H,9-12,14,16H2,1H3,(H,34,39)(H2,35,36,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235562 (1-(4-(5-((4-acetamidopiperidin-1-yl)methyl)pyrrolo...) Show SMILES CC(=O)NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1 Show InChI InChI=1S/C29H29F2N7O4/c1-18(39)34-22-9-11-37(12-10-22)16-20-8-13-38-27(20)28(32-17-33-38)42-25-7-6-23(15-24(25)31)35-29(41)36-26(40)14-19-2-4-21(30)5-3-19/h2-8,13,15,17,22H,9-12,14,16H2,1H3,(H,34,39)(H2,35,36,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system				Bioorg Med Chem Lett 18: 1945-51 (2008) Article DOI: 10.1016/j.bmcl.2008.01.121 BindingDB Entry DOI: 10.7270/Q2125SFV
					More data for this Ligand-Target Pair