BindingDB logo
myBDB logout

null

SMILES: CC(C)Nc1nc2ccc(cc2s1)-c1c(N)[nH]nc1-c1ccccc1F

InChI Key: InChIKey=DTEVYCITSOLYHT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235896   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50235896
PNG
(6-(5-amino-3-(2-fluorophenyl)-1H-pyrazol-4-yl)-N-i...)
Show SMILES CC(C)Nc1nc2ccc(cc2s1)-c1c(N)[nH]nc1-c1ccccc1F
Show InChI InChI=1S/C19H18FN5S/c1-10(2)22-19-23-14-8-7-11(9-15(14)26-19)16-17(24-25-18(16)21)12-5-3-4-6-13(12)20/h3-10H,1-2H3,(H,22,23)(H3,21,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.70n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

Bioorg Med Chem Lett 18: 1874-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.011
BindingDB Entry DOI: 10.7270/Q2H41R5C
More data for this
Ligand-Target Pair