BDBM50236005 CHEMBL4059484

SMILES: CN(C)Cc1ccc(cc1)-c1cc(C#N)c(NCc2ccccc2)n2cnnc12

InChI Key: InChIKey=QLKBCENFIRCWBD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50236005 (CHEMBL4059484) Show SMILES CN(C)Cc1ccc(cc1)-c1cc(C#N)c(NCc2ccccc2)n2cnnc12 Show InChI InChI=1S/C23H22N6/c1-28(2)15-18-8-10-19(11-9-18)21-12-20(13-24)22(29-16-26-27-23(21)29)25-14-17-6-4-3-5-7-17/h3-12,16,25H,14-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged EED (76 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL asses...				J Med Chem 60: 2215-2226 (2017) Article DOI: 10.1021/acs.jmedchem.6b01576 BindingDB Entry DOI: 10.7270/Q20G3NDT
					More data for this Ligand-Target Pair