BDBM50236241 CHEMBL4069050

SMILES: COc1ccc(cc1C)C(=O)N1CCCC(C1)c1cc(C)nc2ncnn12

InChI Key: InChIKey=VSEBQNKGBAFSQB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50236241 (CHEMBL4069050) Show SMILES COc1ccc(cc1C)C(=O)N1CCCC(C1)c1cc(C)nc2ncnn12 Show InChI InChI=1S/C20H23N5O2/c1-13-9-15(6-7-18(13)27-3)19(26)24-8-4-5-16(11-24)17-10-14(2)23-20-21-12-22-25(17)20/h6-7,9-10,12,16H,4-5,8,11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of human full length GST-tagged PDE2a using FAM-labeled cAMP as substrate preincubated for 5 mins followed by substrate addition measured ...				J Med Chem 60: 2037-2051 (2017) Article DOI: 10.1021/acs.jmedchem.6b01793 BindingDB Entry DOI: 10.7270/Q2Q242GF
					More data for this Ligand-Target Pair