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SMILES: Cn1c(cc2sccc12)C(=O)Nc1cccc(Br)c1

InChI Key: InChIKey=DXAZPQWQIMYZIN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236422   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A/REST corepressor 1


(Homo sapiens (Human))		BDBM50236422
PNG
(CHEMBL4068273)
Show SMILES Cn1c(cc2sccc12)C(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C14H11BrN2OS/c1-17-11-5-6-19-13(11)8-12(17)14(18)16-10-4-2-3-9(15)7-10/h2-8H,1H3,(H,16,18)
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Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...

J Med Chem 60: 1673-1692 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01018
BindingDB Entry DOI: 10.7270/Q26112KN
More data for this
Ligand-Target Pair