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BDBM50236793 CHEMBL4064478

SMILES: CCN1CCN(Cc2cn(c3ccc(OC)cc23)S(=O)(=O)c2ccccc2)CC1

InChI Key: InChIKey=NRWCJQOVNWGEOQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50236793
PNG
(CHEMBL4064478)
Show SMILES CCN1CCN(Cc2cn(c3ccc(OC)cc23)S(=O)(=O)c2ccccc2)CC1
Show InChI InChI=1S/C22H27N3O3S/c1-3-23-11-13-24(14-12-23)16-18-17-25(22-10-9-19(28-2)15-21(18)22)29(26,27)20-7-5-4-6-8-20/h4-10,15,17H,3,11-14,16H2,1-2H3
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Similars
Article
PubMed
 8.80n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins

J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair