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BDBM50236816 CHEMBL4070850

SMILES: COc1ccc(cc1)S(=O)(=O)n1cc(CN2CCN(C)CC2)c2cc(OC)ccc12

InChI Key: InChIKey=MLPQPSFNIQXTNE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236816   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50236816
PNG
(CHEMBL4070850)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1cc(CN2CCN(C)CC2)c2cc(OC)ccc12
Show InChI InChI=1S/C22H27N3O4S/c1-23-10-12-24(13-11-23)15-17-16-25(22-9-6-19(29-3)14-21(17)22)30(26,27)20-7-4-18(28-2)5-8-20/h4-9,14,16H,10-13,15H2,1-3H3
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Article
PubMed
 18n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins

J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair