BDBM50236937 CHEMBL4074504
SMILES: CC[C@@H](C)[C@@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1
InChI Key: InChIKey=PCXWJDDQHZSZOQ-UGXUDPGPSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50236937 (CHEMBL4074504) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured... | Eur J Med Chem 129: 110-123 (2017) Article DOI: 10.1016/j.ejmech.2017.02.006 BindingDB Entry DOI: 10.7270/Q2GB269P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50236937 (CHEMBL4074504) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brain | Eur J Med Chem 129: 110-123 (2017) Article DOI: 10.1016/j.ejmech.2017.02.006 BindingDB Entry DOI: 10.7270/Q2GB269P | |||||||||||
More data for this Ligand-Target Pair |