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BDBM50237028 CHEMBL4078113

SMILES: Fc1ccc(CCN(Cc2ccc3OCOc3c2)c2nc(ncc2F)C#N)cc1

InChI Key: InChIKey=ZDFVUZAATQBYIF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237028   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Procathepsin L


(Homo sapiens (Human))		BDBM50237028
PNG
(CHEMBL4078113)
Show SMILES Fc1ccc(CCN(Cc2ccc3OCOc3c2)c2nc(ncc2F)C#N)cc1
Show InChI InChI=1S/C21H16F2N4O2/c22-16-4-1-14(2-5-16)7-8-27(21-17(23)11-25-20(10-24)26-21)12-15-3-6-18-19(9-15)29-13-28-18/h1-6,9,11H,7-8,12-13H2
PDB
MMDB

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Similars
Article
PubMed
 279n/an/an/an/an/an/an/an/a



Roche Pharmaceutical Research and Early Development (pRED)

Curated by ChEMBL


Assay Description
Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retina

J Med Chem 60: 2485-2497 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01881
BindingDB Entry DOI: 10.7270/Q2PV6NN3
More data for this
Ligand-Target Pair