BDBM50237107 CHEMBL4077419

SMILES: Clc1cc(Cl)cc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)c1

InChI Key: InChIKey=FQQXXGPMRNGLEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50237107 (CHEMBL4077419) Show SMILES Clc1cc(Cl)cc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)c1 Show InChI InChI=1S/C21H14BrCl2N5S/c22-12-2-1-3-15(6-12)27-20-18-10-16(4-5-19(18)25-11-26-20)28-21(30)29-17-8-13(23)7-14(24)9-17/h1-11H,(H,25,26,27)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged EGFR (668 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system				J Med Chem 60: 2853-2868 (2017) Article DOI: 10.1021/acs.jmedchem.6b01774 BindingDB Entry DOI: 10.7270/Q2K35WXP
					More data for this Ligand-Target Pair