null

SMILES: Cn1cc(cn1)-c1cccc(c1)-c1cnc(N)c(n1)C(=O)NC1C2CC3CC1CC(O)(C3)C2

InChI Key: InChIKey=KADWYJUBGMHRCN-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50237234 (CHEMBL4103500) Show SMILES Cn1cc(cn1)-c1cccc(c1)-c1cnc(N)c(n1)C(=O)NC1C2CC3CC1CC(O)(C3)C2 |TLB:21:22:28:25.26.31,30:29:22:25.24.26,THB:24:23:28:25.26.31,24:25:28:22.23.32,31:29:22:25.24.26,31:25:22:29.28.32,(1.65,-17.33,;2.55,-18.58,;2.08,-20.05,;3.32,-20.95,;4.57,-20.05,;4.09,-18.58,;3.32,-22.48,;1.99,-23.25,;1.99,-24.8,;3.33,-25.57,;4.65,-24.8,;4.66,-23.25,;5.98,-25.57,;5.98,-27.11,;7.32,-27.88,;8.66,-27.11,;9.99,-27.88,;8.65,-25.56,;7.31,-24.8,;9.98,-24.78,;11.32,-25.55,;9.97,-23.24,;11.3,-22.47,;12.8,-22.05,;14.21,-22.61,;15.22,-21.34,;13.82,-21.68,;12.5,-21.19,;12.49,-19.7,;13.83,-19.23,;13.82,-17.69,;15.24,-19.81,;12.8,-20.47,)| Show InChI InChI=1S/C25H28N6O2/c1-31-13-19(11-28-31)15-3-2-4-16(7-15)20-12-27-23(26)22(29-20)24(32)30-21-17-5-14-6-18(21)10-25(33,8-14)9-17/h2-4,7,11-14,17-18,21,33H,5-6,8-10H2,1H3,(H2,26,27)(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...				Bioorg Med Chem Lett 27: 1776-1779 (2017) Article DOI: 10.1016/j.bmcl.2017.02.060 BindingDB Entry DOI: 10.7270/Q2H41TQC
					More data for this Ligand-Target Pair				3D Structure (crystal)