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SMILES: Cc1nc2cc(C)ccn2c1-c1csc(Nc2cc(C)ccn2)n1

InChI Key: InChIKey=DVFMVZSPYIULMB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237245   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM50237245
PNG
(CHEMBL4104855)
Show SMILES Cc1nc2cc(C)ccn2c1-c1csc(Nc2cc(C)ccn2)n1
Show InChI InChI=1S/C18H17N5S/c1-11-4-6-19-15(8-11)22-18-21-14(10-24-18)17-13(3)20-16-9-12(2)5-7-23(16)17/h4-10H,1-3H3,(H,19,21,22)
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Article
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n/an/a 1.90E+3n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...

Bioorg Med Chem Lett 27: 1776-1779 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.060
BindingDB Entry DOI: 10.7270/Q2H41TQC
More data for this
Ligand-Target Pair