null

SMILES: CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key: InChIKey=POYJJGBBXYWWNI-OAQYLSRUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50237550 (CHEMBL4091010) Show SMILES CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r| Show InChI InChI=1S/C25H30BrN5O3/c1-15(2)11-21(31-24(33)34-25(3,4)5)23(32)30-18-9-10-20-19(13-18)22(28-14-27-20)29-17-8-6-7-16(26)12-17/h6-10,12-15,21H,11H2,1-5H3,(H,30,32)(H,31,33)(H,27,28,29)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Xuzhou Medical University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) measured after 40 mins by Kinase Glo luminescence assay				Eur J Med Chem 130: 393-405 (2017) Article DOI: 10.1016/j.ejmech.2017.02.061 BindingDB Entry DOI: 10.7270/Q21Z46PJ
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50237550 (CHEMBL4091010) Show SMILES CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 |r| Show InChI InChI=1S/C25H30BrN5O3/c1-15(2)11-21(31-24(33)34-25(3,4)5)23(32)30-18-9-10-20-19(13-18)22(28-14-27-20)29-17-8-6-7-16(26)12-17/h6-10,12-15,21H,11H2,1-5H3,(H,30,32)(H,31,33)(H,27,28,29)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xuzhou Medical University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) measured after 40 mins by Kinase Glo luminescence assay				Eur J Med Chem 130: 393-405 (2017) Article DOI: 10.1016/j.ejmech.2017.02.061 BindingDB Entry DOI: 10.7270/Q21Z46PJ
					More data for this Ligand-Target Pair