BDBM50237956 1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-tetrazol-5-ylthio)ethanone::CHEMBL254255::cid_1515366

SMILES: COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1

InChI Key: InChIKey=GDWOAVFPULCMCY-UHFFFAOYSA-N

Data: 8 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50237956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2JQ0ZDS
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2MS3R5M
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RRG
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q20863Q9
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of TNAP by analogous luminescence assay				Bioorg Med Chem 18: 573-9 (2010) Article DOI: 10.1016/j.bmc.2009.12.012 BindingDB Entry DOI: 10.7270/Q24T6JHR
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.99E+5	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2RV0M49
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 4A3 (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem Lett 18: 2250-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.013 BindingDB Entry DOI: 10.7270/Q26Q1X08
					More data for this Ligand-Target Pair
Phospholipase A-2-activating protein (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of PLAP by analogous luminescence assay				Bioorg Med Chem 18: 573-9 (2010) Article DOI: 10.1016/j.bmc.2009.12.012 BindingDB Entry DOI: 10.7270/Q24T6JHR
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM50237956 (1-(3,4-dihydroxyphenyl)-2-(1-(4-methoxyphenyl)-1H-...) Show SMILES COc1ccc(cc1)-n1nnnc1SCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-3-11(4-6-12)20-16(17-18-19-20)25-9-15(23)10-2-7-13(21)14(22)8-10/h2-8,21-22H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q29S1PG8
					More data for this Ligand-Target Pair