null

SMILES: CS(=O)(=O)N1CCC(C1)C(O)c1cncnc1Nc1ccc(F)cc1

InChI Key: InChIKey=NMQSZTPFFUGIPB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50238119 (CHEMBL4075207) Show SMILES CS(=O)(=O)N1CCC(C1)C(O)c1cncnc1Nc1ccc(F)cc1 Show InChI InChI=1S/C16H19FN4O3S/c1-25(23,24)21-7-6-11(9-21)15(22)14-8-18-10-19-16(14)20-13-4-2-12(17)3-5-13/h2-5,8,10-11,15,22H,6-7,9H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi-Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against rat adenylate kinase II was determined in the presence of AMP, competitive inhibition				Bioorg Med Chem Lett 27: 1902-1906 (2017) Article DOI: 10.1016/j.bmcl.2017.03.034 BindingDB Entry DOI: 10.7270/Q2KS6TTS
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Mus musculus)	BDBM50238119 (CHEMBL4075207) Show SMILES CS(=O)(=O)N1CCC(C1)C(O)c1cncnc1Nc1ccc(F)cc1 Show InChI InChI=1S/C16H19FN4O3S/c1-25(23,24)21-7-6-11(9-21)15(22)14-8-18-10-19-16(14)20-13-4-2-12(17)3-5-13/h2-5,8,10-11,15,22H,6-7,9H2,1H3,(H,18,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi-Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...				Bioorg Med Chem Lett 27: 1902-1906 (2017) Article DOI: 10.1016/j.bmcl.2017.03.034 BindingDB Entry DOI: 10.7270/Q2KS6TTS
					More data for this Ligand-Target Pair