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SMILES: CC(=O)C1=CN(Cc2ccccc2C)C=CC1CC1Cc2cc(C)ccc2C1=O

InChI Key: InChIKey=FDNONNIZVXIZQU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))		BDBM50238232
PNG
(CHEMBL4083445)
Show SMILES CC(=O)C1=CN(Cc2ccccc2C)C=CC1CC1Cc2cc(C)ccc2C1=O |c:15,t:3|
Show InChI InChI=1S/C26H27NO2/c1-17-8-9-24-22(12-17)14-23(26(24)29)13-20-10-11-27(16-25(20)19(3)28)15-21-7-5-4-6-18(21)2/h4-12,16,20,23H,13-15H2,1-3H3
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MMDB

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Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



VFP Therapies

Curated by ChEMBL


Assay Description
Inhibition of AChE in human erythrocytes using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured ...

J Med Chem 60: 5909-5926 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00702
BindingDB Entry DOI: 10.7270/Q22V2JC5
More data for this
Ligand-Target Pair