BDBM50238310 CHEMBL4100492

SMILES: Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12

InChI Key: InChIKey=PDSSQGHYCJMBBM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238310 (CHEMBL4100492) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C22H21N5O/c1-15-20-19(12-14-23-21(20)27-26-15)17-7-9-18(10-8-17)25-22(28)24-13-11-16-5-3-2-4-6-16/h2-10,12,14H,11,13H2,1H3,(H,23,26,27)(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238310 (CHEMBL4100492) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C22H21N5O/c1-15-20-19(12-14-23-21(20)27-26-15)17-7-9-18(10-8-17)25-22(28)24-13-11-16-5-3-2-4-6-16/h2-10,12,14H,11,13H2,1H3,(H,23,26,27)(H2,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50238310 (CHEMBL4100492) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C22H21N5O/c1-15-20-19(12-14-23-21(20)27-26-15)17-7-9-18(10-8-17)25-22(28)24-13-11-16-5-3-2-4-6-16/h2-10,12,14H,11,13H2,1H3,(H,23,26,27)(H2,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair