BDBM50238364 CHEMBL4064008
SMILES: COc1ccc(OC[C@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1
InChI Key: InChIKey=UDKWTIUVZOIYNA-AREMUKBSSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat)) | BDBM50238364 (CHEMBL4064008) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ... | J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT) | BDBM50238364 (CHEMBL4064008) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ... | J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ionotropic glutamate receptor NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50238364 (CHEMBL4064008) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ... | J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H | |||||||||||
More data for this Ligand-Target Pair |