BDBM50238456 CHEMBL4092132

SMILES: Clc1cccc(-c2nc(cs2)C(=O)N2CCCCC2)c1Cl

InChI Key: InChIKey=SWPGMAMLXBDJQI-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238456 (CHEMBL4092132) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCCCC2)c1Cl Show InChI InChI=1S/C15H14Cl2N2OS/c16-11-6-4-5-10(13(11)17)14-18-12(9-21-14)15(20)19-7-2-1-3-8-19/h4-6,9H,1-3,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238456 (CHEMBL4092132) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCCCC2)c1Cl Show InChI InChI=1S/C15H14Cl2N2OS/c16-11-6-4-5-10(13(11)17)14-18-12(9-21-14)15(20)19-7-2-1-3-8-19/h4-6,9H,1-3,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238456 (CHEMBL4092132) Show SMILES Clc1cccc(-c2nc(cs2)C(=O)N2CCCCC2)c1Cl Show InChI InChI=1S/C15H14Cl2N2OS/c16-11-6-4-5-10(13(11)17)14-18-12(9-21-14)15(20)19-7-2-1-3-8-19/h4-6,9H,1-3,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair