BDBM50238525 CHEMBL4106291

SMILES: [H][C@]12COP(O)(=O)OP([O-])(=O)OC[C@@]3([H])S[C@]([H])([C@H](O)[C@@H]3O)[n+]3cnc4n(cnc4c3N)[C@]([H])(O1)[C@H](O)[C@@H]2O

InChI Key: InChIKey=HPEIZBPCFYXASL-KEOHHSTQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor (Hemicentrotus pulcherrimus)	BDBM50238525 (CHEMBL4106291) Show SMILES [H][C@]12COP(O)(=O)OP([O-])(=O)OC[C@@]3([H])S[C@]([H])([C@H](O)[C@@H]3O)[n+]3cnc4n(cnc4c3N)[C@]([H])(O1)[C@H](O)[C@@H]2O |r| Show InChI InChI=1S/C15H21N5O12P2S/c16-12-7-13-18-4-19(12)15-11(24)9(22)6(35-15)2-30-34(27,28)32-33(25,26)29-1-5-8(21)10(23)14(31-5)20(13)3-17-7/h3-6,8-11,14-16,21-24H,1-2H2,(H2,25,26,27,28)/t5-,6-,8-,9-,10-,11-,14-,15-/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Juntendo University School of Medicine Curated by ChEMBL					Assay Description Agonist activity at ryanodine receptor in Hemicentrotus pulcherrimus egg homogenate assessed as increase in intracellular calcium mobilization by Flu...				J Med Chem 60: 5868-5875 (2017) Article DOI: 10.1021/acs.jmedchem.7b00540 BindingDB Entry DOI: 10.7270/Q2NK3H9R
					More data for this Ligand-Target Pair