BDBM50238771 CHEMBL4087858

SMILES: Cl.COc1ccc(F)cc1C1CC1CNC1(CC1)c1ccccc1OC

InChI Key: InChIKey=CLEHPHXIWRHWIS-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238771 (CHEMBL4087858) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNC1(CC1)c1ccccc1OC Show InChI InChI=1S/C21H24FNO2.ClH/c1-24-19-8-7-15(22)12-17(19)16-11-14(16)13-23-21(9-10-21)18-5-3-4-6-20(18)25-2;/h3-8,12,14,16,23H,9-11,13H2,1-2H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	661	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238771 (CHEMBL4087858) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNC1(CC1)c1ccccc1OC Show InChI InChI=1S/C21H24FNO2.ClH/c1-24-19-8-7-15(22)12-17(19)16-11-14(16)13-23-21(9-10-21)18-5-3-4-6-20(18)25-2;/h3-8,12,14,16,23H,9-11,13H2,1-2H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	655	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of binding of 1 nM N6-[3H]cyclohexyladenosine to adenosine A1 receptor on rat cerebral cortical membranes.				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238771 (CHEMBL4087858) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNC1(CC1)c1ccccc1OC Show InChI InChI=1S/C21H24FNO2.ClH/c1-24-19-8-7-15(22)12-17(19)16-11-14(16)13-23-21(9-10-21)18-5-3-4-6-20(18)25-2;/h3-8,12,14,16,23H,9-11,13H2,1-2H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	874	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238771 (CHEMBL4087858) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNC1(CC1)c1ccccc1OC Show InChI InChI=1S/C21H24FNO2.ClH/c1-24-19-8-7-15(22)12-17(19)16-11-14(16)13-23-21(9-10-21)18-5-3-4-6-20(18)25-2;/h3-8,12,14,16,23H,9-11,13H2,1-2H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	871	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair