BDBM50238848 CHEMBL4103327

SMILES: Oc1ccc(Cc2[nH]c(-c3cc(Cl)ccn3)c3c2oc2ccccc2c3=O)cc1

InChI Key: InChIKey=GABGPSOOCLUCEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50238848 (CHEMBL4103327) Show SMILES Oc1ccc(Cc2[nH]c(-c3cc(Cl)ccn3)c3c2oc2ccccc2c3=O)cc1 Show InChI InChI=1S/C23H15ClN2O3/c24-14-9-10-25-17(12-14)21-20-22(28)16-3-1-2-4-19(16)29-23(20)18(26-21)11-13-5-7-15(27)8-6-13/h1-10,12,26-27H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University Curated by ChEMBL					Assay Description Inhibition of PDE5A1 catalytic domain (535 to 860 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]cGMP as substrate afte...				J Med Chem 60: 6622-6637 (2017) Article DOI: 10.1021/acs.jmedchem.7b00523 BindingDB Entry DOI: 10.7270/Q23N25NF
					More data for this Ligand-Target Pair