BDBM50238981 CHEMBL4073079

SMILES: Cc1[nH]c(C(=O)Nc2ccc(Nc3nc(no3)C(O)=O)cc2)c(Cl)c1Cl

InChI Key: InChIKey=NJJHNMBWKZOBQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase (Staphylococcus aureus)	BDBM50238981 (CHEMBL4073079) Show SMILES Cc1[nH]c(C(=O)Nc2ccc(Nc3nc(no3)C(O)=O)cc2)c(Cl)c1Cl Show InChI InChI=1S/C15H11Cl2N5O4/c1-6-9(16)10(17)11(18-6)13(23)19-7-2-4-8(5-3-7)20-15-21-12(14(24)25)22-26-15/h2-5,18H,1H3,(H,19,23)(H,24,25)(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase A/DNA gyrase B supercoiling activity using relaxed pNO1 DNA as substrate after 30 mins in presence of ...				Eur J Med Chem 130: 171-184 (2017) Article DOI: 10.1016/j.ejmech.2017.02.046 BindingDB Entry DOI: 10.7270/Q22N54KZ
					More data for this Ligand-Target Pair