BDBM50239132 CHEMBL4095219

SMILES: Fc1ccc(cc1)S(=O)(=O)Nc1ccncc1-c1ccc(cc1)C#N

InChI Key: InChIKey=AMUOVZOGACNWEZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50239132 (CHEMBL4095219) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccncc1-c1ccc(cc1)C#N Show InChI InChI=1S/C18H12FN3O2S/c19-15-5-7-16(8-6-15)25(23,24)22-18-9-10-21-12-17(18)14-3-1-13(11-20)2-4-14/h1-10,12H,(H,21,22)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...				Bioorg Med Chem Lett 27: 1919-1922 (2017) Article DOI: 10.1016/j.bmcl.2017.03.041 BindingDB Entry DOI: 10.7270/Q2NK3H6D
					More data for this Ligand-Target Pair