BDBM50239258 CHEMBL4070727

SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](OC(F)F)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1

InChI Key: InChIKey=KFNBODGMHYCMQN-GVMRPCBKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50239258 (CHEMBL4070727) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](OC(F)F)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 |r| Show InChI InChI=1S/C22H23ClF2O7/c1-2-29-15-6-3-12(4-7-15)9-13-10-14(5-8-16(13)23)22-19(28)17(26)18(27)21(32-22,11-30-22)31-20(24)25/h3-8,10,17-20,26-28H,2,9,11H2,1H3/t17-,18-,19+,21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
Haisco Pharmaceuticals Group Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount method				J Med Chem 60: 4173-4184 (2017) Article DOI: 10.1021/acs.jmedchem.6b01818 BindingDB Entry DOI: 10.7270/Q2W37ZFS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50239258 (CHEMBL4070727) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](OC(F)F)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 |r| Show InChI InChI=1S/C22H23ClF2O7/c1-2-29-15-6-3-12(4-7-15)9-13-10-14(5-8-16(13)23)22-19(28)17(26)18(27)21(32-22,11-30-22)31-20(24)25/h3-8,10,17-20,26-28H,2,9,11H2,1H3/t17-,18-,19+,21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Haisco Pharmaceuticals Group Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount method				J Med Chem 60: 4173-4184 (2017) Article DOI: 10.1021/acs.jmedchem.6b01818 BindingDB Entry DOI: 10.7270/Q2W37ZFS
					More data for this Ligand-Target Pair