BDBM50239260 CHEMBL4090131

SMILES: CCOc1ccc(Cc2cccc(c2)[C@]23OC[C@](OC)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1

InChI Key: InChIKey=MLZFALOQUWECAD-CUUWFGFTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50239260 (CHEMBL4090131) Show SMILES CCOc1ccc(Cc2cccc(c2)[C@]23OC[C@](OC)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 |r| Show InChI InChI=1S/C22H26O7/c1-3-27-17-9-7-14(8-10-17)11-15-5-4-6-16(12-15)22-20(25)18(23)19(24)21(26-2,29-22)13-28-22/h4-10,12,18-20,23-25H,3,11,13H2,1-2H3/t18-,19-,20+,21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Haisco Pharmaceuticals Group Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount method				J Med Chem 60: 4173-4184 (2017) Article DOI: 10.1021/acs.jmedchem.6b01818 BindingDB Entry DOI: 10.7270/Q2W37ZFS
					More data for this Ligand-Target Pair