BDBM50239431 CHEMBL4069000

SMILES: FC(F)(F)Oc1ccccc1NC(=O)c1c(NC(=O)C(F)(F)I)sc2CCCc12

InChI Key: InChIKey=NOPPZLYTYWAODZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anoctamin-1 (Homo sapiens (Human))	BDBM50239431 (CHEMBL4069000) Show SMILES FC(F)(F)Oc1ccccc1NC(=O)c1c(NC(=O)C(F)(F)I)sc2CCCc12 Show InChI InChI=1S/C17H12F5IN2O3S/c18-16(19,23)15(27)25-14-12(8-4-3-7-11(8)29-14)13(26)24-9-5-1-2-6-10(9)28-17(20,21)22/h1-2,5-6H,3-4,7H2,(H,24,26)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...				J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G
					More data for this Ligand-Target Pair