BDBM50239461 CHEMBL4074900

SMILES: FC(F)(Br)C(=O)Nc1sc2CCCCCc2c1C(=O)Nc1ccccc1

InChI Key: InChIKey=GAZFNWXLZNWENT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anoctamin-1 (Homo sapiens (Human))	BDBM50239461 (CHEMBL4074900) Show SMILES FC(F)(Br)C(=O)Nc1sc2CCCCCc2c1C(=O)Nc1ccccc1 Show InChI InChI=1S/C18H17BrF2N2O2S/c19-18(20,21)17(25)23-16-14(12-9-5-2-6-10-13(12)26-16)15(24)22-11-7-3-1-4-8-11/h1,3-4,7-8H,2,5-6,9-10H2,(H,22,24)(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...				J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G
					More data for this Ligand-Target Pair