BDBM50239566 CHEMBL4103140

SMILES: CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)N(CCc1ccc(OC)cc1)C3

InChI Key: InChIKey=MWNUDTXWOMXGKW-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50239566 (CHEMBL4103140) Show SMILES CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)N(CCc1ccc(OC)cc1)C3 |c:5| Show InChI InChI=1S/C27H28N4O4/c1-4-31-24-23(25(32)29-27(31)34)21(18-9-5-16(2)6-10-18)22-20(28-24)15-30(26(22)33)14-13-17-7-11-19(35-3)12-8-17/h5-12,21,28H,4,13-15H2,1-3H3,(H,29,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of BI-BODIPY binding to BRD4 bromodomain 1 (42 to 168 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence an...				J Med Chem 60: 4805-4817 (2017) Article DOI: 10.1021/acs.jmedchem.6b01336 BindingDB Entry DOI: 10.7270/Q2PC34JK
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50239566 (CHEMBL4103140) Show SMILES CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)N(CCc1ccc(OC)cc1)C3 |c:5| Show InChI InChI=1S/C27H28N4O4/c1-4-31-24-23(25(32)29-27(31)34)21(18-9-5-16(2)6-10-18)22-20(28-24)15-30(26(22)33)14-13-17-7-11-19(35-3)12-8-17/h5-12,21,28H,4,13-15H2,1-3H3,(H,29,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of BI-BODIPY binding to BRDT bromodomain 1 (29 to 134 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence a...				J Med Chem 60: 4805-4817 (2017) Article DOI: 10.1021/acs.jmedchem.6b01336 BindingDB Entry DOI: 10.7270/Q2PC34JK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50239566 (CHEMBL4103140) Show SMILES CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)N(CCc1ccc(OC)cc1)C3 |c:5| Show InChI InChI=1S/C27H28N4O4/c1-4-31-24-23(25(32)29-27(31)34)21(18-9-5-16(2)6-10-18)22-20(28-24)15-30(26(22)33)14-13-17-7-11-19(35-3)12-8-17/h5-12,21,28H,4,13-15H2,1-3H3,(H,29,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of BI-BODIPY binding to BRD4 bromodomain 1 (42 to 168 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence an...				J Med Chem 60: 4805-4817 (2017) Article DOI: 10.1021/acs.jmedchem.6b01336 BindingDB Entry DOI: 10.7270/Q2PC34JK
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50239566 (CHEMBL4103140) Show SMILES CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)N(CCc1ccc(OC)cc1)C3 |c:5| Show InChI InChI=1S/C27H28N4O4/c1-4-31-24-23(25(32)29-27(31)34)21(18-9-5-16(2)6-10-18)22-20(28-24)15-30(26(22)33)14-13-17-7-11-19(35-3)12-8-17/h5-12,21,28H,4,13-15H2,1-3H3,(H,29,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of BI-BODIPY binding to BRDT bromodomain 1 (29 to 134 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence a...				J Med Chem 60: 4805-4817 (2017) Article DOI: 10.1021/acs.jmedchem.6b01336 BindingDB Entry DOI: 10.7270/Q2PC34JK
					More data for this Ligand-Target Pair