BDBM50240298 CHEMBL4092652

SMILES: CN1CCCCOc2ccnc3[nH]c(=O)n(-c4nc1ccc4Cl)c23

InChI Key: InChIKey=YXMJUUARHWYXHZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50240298 (CHEMBL4092652) Show SMILES CN1CCCCOc2ccnc3[nH]c(=O)n(-c4nc1ccc4Cl)c23 Show InChI InChI=1S/C16H16ClN5O2/c1-21-8-2-3-9-24-11-6-7-18-14-13(11)22(16(23)20-14)15-10(17)4-5-12(21)19-15/h4-7H,2-3,8-9H2,1H3,(H,18,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...				Bioorg Med Chem Lett 27: 2497-2501 (2017) Article DOI: 10.1016/j.bmcl.2017.03.099 BindingDB Entry DOI: 10.7270/Q21G0PCZ
					More data for this Ligand-Target Pair