BindingDB PrimarySearch

BDBM50240801 CHEMBL131967::N-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yl)benzamide::N-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzamide::N-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-benzamide::N-(phenylcarbonyl)-beta-D-glucopyranosylamine

SMILES: OC[C@H]1O[C@@H](NC(=O)c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=SPYSOSUFGSNSMY-BZNQNGANSA-N

Data: 14 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50240801
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Competitive inhibition of rabbit muscle glycogen phosphorylase b				ACS Med Chem Lett 4: 612-5 (2013) Article DOI: 10.1021/ml4001529 BindingDB Entry DOI: 10.7270/Q2X068FD
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit skeletal muscle glycogen phosphorylase b				Bioorg Med Chem 18: 1171-80 (2010) Article DOI: 10.1016/j.bmc.2009.12.043 BindingDB Entry DOI: 10.7270/Q2JQ114D
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibitory activity against muscle Glycogen Phosphorylase b				J Med Chem 44: 2843-8 (2001) BindingDB Entry DOI: 10.7270/Q2NV9JZQ
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of rabbit glycogen phosphorylase B enzyme				J Med Chem 40: 1455-64 (1997) Article DOI: 10.1021/jm9608016 BindingDB Entry DOI: 10.7270/Q26T0N9N
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase b				Eur J Med Chem 76: 567-79 (2014) Article DOI: 10.1016/j.ejmech.2014.02.041 BindingDB Entry DOI: 10.7270/Q2ZP47N4
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Thessaly Curated by ChEMBL					Assay Description Inhibition of rabbit skeletal muscle glycogen phosphorylase b assessed as inorganic phosphate release				Bioorg Med Chem 22: 4810-25 (2014) Article DOI: 10.1016/j.bmc.2014.06.058 BindingDB Entry DOI: 10.7270/Q2KS6T58
University of Thessaly Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase b				Bioorg Med Chem Lett 18: 5680-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.052 BindingDB Entry DOI: 10.7270/Q2571BTV
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase b				Bioorg Med Chem 17: 4773-85 (2009) Article DOI: 10.1016/j.bmc.2009.04.036 BindingDB Entry DOI: 10.7270/Q2Q52PPV
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibitory binding constant against glycogen phosphorylase B				J Med Chem 47: 3075-88 (2004) Article DOI: 10.1021/jm030586a BindingDB Entry DOI: 10.7270/Q2930TXG
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release at pH 6.8				Bioorg Med Chem 20: 1801-16 (2012) Article DOI: 10.1016/j.bmc.2011.12.059 BindingDB Entry DOI: 10.7270/Q2SN09DD
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit skeletal muscle glycogen phosphorylase b by Lineweaver-Burk plot method				Bioorg Med Chem 21: 5738-47 (2013) Article DOI: 10.1016/j.bmc.2013.07.024 BindingDB Entry DOI: 10.7270/Q2BC410F
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	8.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alcala Curated by ChEMBL					Assay Description Inhibitory activity against rabbit muscle glycogen phosphorylase				J Med Chem 40: 4089-102 (1998) Checked by Author Article DOI: 10.1021/jm970273d BindingDB Entry DOI: 10.7270/Q2S46TGM
University of Alcala Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibition of rabbit skeletal muscle glycogen phosphorylase b				Bioorg Med Chem 18: 1171-80 (2010) Article DOI: 10.1016/j.bmc.2009.12.043 BindingDB Entry DOI: 10.7270/Q2JQ114D
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM50240801 (CHEMBL131967 \| N-((2R,3R,4S,5S,6R)-3,4,5-trihydrox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PubMed	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibitory activity against muscle Glycogen Phosphorylase b				J Med Chem 44: 2843-8 (2001) BindingDB Entry DOI: 10.7270/Q2NV9JZQ
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair