BDBM50240856 7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]heptane

SMILES: CN1C2CCC1C(C2)c1ccnnc1

InChI Key: InChIKey=CZOBPXOJOUBLHR-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50240856 (7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]hept...) Show SMILES CN1C2CCC1C(C2)c1ccnnc1 |TLB:8:6:1:4.3| Show InChI InChI=1S/C11H15N3/c1-14-9-2-3-11(14)10(6-9)8-4-5-12-13-7-8/h4-5,7,9-11H,2-3,6H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Effective concentration against Nicotinic acetylcholine receptor alpha 7				J Med Chem 48: 4705-45 (2005) Article DOI: 10.1021/jm040219e BindingDB Entry DOI: 10.7270/Q29W0G79
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50240856 (7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]hept...) Show SMILES CN1C2CCC1C(C2)c1ccnnc1 |TLB:8:6:1:4.3| Show InChI InChI=1S/C11H15N3/c1-14-9-2-3-11(14)10(6-9)8-4-5-12-13-7-8/h4-5,7,9-11H,2-3,6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Effective concentration against Nicotinic acetylcholine receptor alpha4-beta2				J Med Chem 48: 4705-45 (2005) Article DOI: 10.1021/jm040219e BindingDB Entry DOI: 10.7270/Q29W0G79
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM50240856 (7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]hept...) Show SMILES CN1C2CCC1C(C2)c1ccnnc1 |TLB:8:6:1:4.3| Show InChI InChI=1S/C11H15N3/c1-14-9-2-3-11(14)10(6-9)8-4-5-12-13-7-8/h4-5,7,9-11H,2-3,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2				J Med Chem 48: 4705-45 (2005) Article DOI: 10.1021/jm040219e BindingDB Entry DOI: 10.7270/Q29W0G79
					More data for this Ligand-Target Pair