BDBM50241196 (R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine

SMILES: C[C@@H](c1cnc[nH]1)c1cccc(C)c1C

InChI Key: InChIKey=CUHVIMMYOGQXCV-LLVKDONJSA-N

Data: 23 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50241196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
adrenergic Alpha2 (RAT)	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.00	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
ADRA2A (MOUSE)	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP Ki Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	13.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP Ki Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	15.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	19.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	33.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP Ki Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
					More data for this Ligand-Target Pair
Imidazoline I1 (RAT)	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	95.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP Ki Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
					More data for this Ligand-Target Pair
Imidazoline I1 (BOVINE)	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50241196 ((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...) Show SMILES C[C@@H](c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Croissy Curated by PDSP Ki Database									J Pharmacol Exp Ther 295: 1192-205 (2000) BindingDB Entry DOI: 10.7270/Q28P5Z2C
					More data for this Ligand-Target Pair